While some celebrities, like Kyle Richards, have denied using the Type 2 diabetes drug, which is usually taken once a week via an injection in the stomach, thigh, or under the arm, some have admitted to using the medication in their weight loss journey.
From Elon Musk to Chelsea Handler, some celebrities have confessed to using Ozempic and other GLP-1 medications for their weight loss.
Amanda Bynes
In December 2025, Amanda Bynes revealed to her fans and followers that she had lost 28 pounds since taking Ozempic. She posted a paparazzi photo and told her fans and followers that she weighed 152 pounds after losing 28 pounds.
She told her fans and followers that she still felt like she was “big” in the photo, which was motivating and inspiring to her.
Amanda Bynes has been very open and honest with her fans and followers about her struggles with her weight. Bynes told her fans and followers in her heyday that she was an addict of Adderall and used the drug for years to keep her weight at a certain size.
In March 2024, Amanda Bynes admitted to her fans and followers on Instagram that she gained over 20 pounds in a short period of time due to depression.
Vanessa Williams
In January 2026, Vanessa Williams revealed in an interview with the magazine Hello! that she had been using Mounjaro to combat menopause-related weight gain over the past two years.
At the age of 62, the actress considers the treatment a turning point in her life. She said that when she turned 60, she started thinking about the future and wanted to be healthy and look great while at it.
Andy Cohen
Andy Cohen told his fans and followers on his SiriusXM show “Andy Cohen Live” on September 9, 2025, that he lost a lot of weight after taking what he called “micro-dosing” of a GLP-1.
According to Cohen, he had been unhappy with his weight and had been in discussions with his doctor, who recommended a GLP-1, not only for weight loss but to help remove plaque in the arteries and to help manage high blood pressure.
He did not, however, specify the drug, but he did indicate that it had more benefits for one’s health, which ultimately contributed to his decision.
He further noted that the drug had greatly reduced his cravings, something he had been struggling with for a while, and that it had made him more disciplined in his diet and exercise routine.
Serena Williams
This professional tennis player has also confessed to using a GLP-1 drug, referred to as Ro, to help her lose over 30 pounds.
Speaking to People magazine in July 2025, Williams noted that she had been feeling much better, both physically and mentally, after using the drug.
According to Williams, she had been struggling with her weight after delivering her daughter, Alexis Olympia, through an emergency C-section in 2017.
Despite maintaining an elite fitness regimen and a healthy diet, she noted that she had been unable to return to her desired weight.
Williams noted that it had been a frustrating experience, especially because she had always been a disciplined person who relied on hard work to maintain fitness and a healthy weight.
This was, however, the first time that hard work and a healthy lifestyle had failed to deliver, and she had to consider medical interventions to help her lose weight.
Brooks Nader
Brooks Nader has also talked about the use of weight loss medication in her life. In her reality television series, “Love Thy Nader,” she talked about the use of a GLP-1 medication, stating that she “microdoses” the medication.
After the release of the television series, Nader talked about the use of the medication and the changes she has gone through, stating that she has more to work on than the use of the medication for weight loss. She also talked about her self-image, stating that the way she feels about her body has changed compared to the way she felt about her body previously.
Renee Graziano
The reality star posted on social media on May 5, 2025, to announce the milestone, saying she had lost 52 pounds. Renee Graziano stated that she enjoys sharing her weight loss journey with her fans because, behind the scenes, she had been very hard on herself. Renee posted pictures of herself, showing how she had changed over the years.
She also discussed the mental aspect of her weight loss journey, saying she had been very hard on herself for years, frustrated by her inability to lose the extra weight she had been carrying.
Renee Graziano said she had some days when she had resorted to food to try and lift her mood, but she realized that it did not make her feel better. She felt like she had been failing to meet expectations from people about how she ought to look and the kind of life she ought to lead based on what society expected of her.
She had been having a weekly injection of the drug Mounjaro for the past five months, and she had also been taking some supplements and having therapy.
She also touched on the subject of cosmetic surgery, saying she had not felt the need to go under the knife to look younger.
Renee Graziano, however, said she understood that people had to do what they felt worked for them, but they had to do it in a healthy manner. The reality star confessed to having some minor surgery like having some Botox and some lip fillers.
She concluded by saying she felt younger and better than she had felt in years after losing a significant amount of weight.
Meghan Trainor
Meghan Trainor revealed she has been using the Mounjaro injection while talking about her recent weight loss on Instagram on March 31, 2025.
She said she has been using the injection and other forms of support to help her get into the shape she wants and to be her “healthiest, strongest” version. She also stated she has been working with a registered dietitian and a personal trainer.
Fat Joe
Fat Joe discussed how he used Ozempic in his weight loss journey in an interview with Us Weekly on October 14, 2024. He used Ozempic to help him achieve his weight loss target of 200 pounds.
The rapper explained that Ozempic helped him control his portions. He said that the medication ensured that he took only a few bites of his favorite foods and apart from using the medication, he also learned the importance of being aware of his diet.
He explained that he now makes sure that he takes fewer carbohydrates. He said that he avoided bread, pasta, and rice in his weight loss journey, while controlling his portions. He now takes fewer portions in his breakfast, which he wouldn’t have done in the past.
Kathy Bates
Kathy Bates said that she lost 20 pounds using Ozempic in October 2024 and this was after losing 80 pounds by changing her lifestyle.
Kathy said that although people thought that Ozempic helped her achieve her weight loss target, her weight loss journey took years and it started all during the pandemic.
She decided to change her lifestyle after being diagnosed with Type 2 diabetes. She used to eat comfort foods such as burgers and pizza to cope with emotional issues. Bates said that diabetes runs in her family and that she saw how it affected her loved ones. It was the fear of diabetes that helped her change her lifestyle.
Macy Gray
Macy Gray talked about her Ozempic weight loss experience on the reality TV show “Surreal Life: Villa of Secrets” in July 2024. She said on the show that she was experiencing stomach pain and constipation after using the medication.
Macy Gray talked about how vanity was a reason why she was using the medication during a confessional on the reality TV show. She was not happy with the way she looked and was looking for a quick solution to lose weight so she could look better on the TV show.
She explained how she got into a dark place emotionally, stopped healthy behaviors, and used food to cope.
Braunwyn Windham-Burke
In June 2024, former Real Housewives of Orange County star Braunwyn Windham-Burke announced that she has been using Ozempic after moving to Nashville with her boyfriend Jennifer Spinner.
When asked about her decision to take the medication during an interview with Us Weekly, Braunwyn Windham-Burke explained that after moving to Nashville and being around Southern foods such as biscuits and fried chicken, she gained 20 pounds. Braunwyn Windham-Burke said that she is someone who cannot control herself around certain foods.
While Braunwyn Windham-Burke did not reveal how much weight she has lost on the medication, she said that the medication was part of her process to take control of her health during a challenging time in her life.
Kelly Clarkson
Kelly Clarkson revealed in May 2024 that she had lost 60 pounds with the help of a weight loss drug.
During a chat with Whoopi Goldberg on The Kelly Clarkson Show, Clarkson said that she had finally resorted to a drug after the results of her blood tests had started to get alarming.
Clarkson stated that people assume that the drug was Ozempic; however, she had used another drug that enables the body to more efficiently process sugar.
Tori Spelling
The actress disclosed that she took the medications Ozempic and Mounjaro in an attempt to reduce her weight after the arrival of her sixth child with Dean McDermott.
During an episode of her podcast, Misspelling, on April 16, Spelling confessed to having taken the medication Mounjaro. She said that many people are now talking openly about the medication.
The actress from the 1990s TV show “Beverly Hills, 90210,” said she had previously taken the medication Ozempic but claimed the medication did not work for her.
She weighed 160 pounds when she started using the medication for weight loss and she wanted to return to her previous weight of 120 pounds. Spelling stopped using the medication Mounjaro in January 2024 after she attained her desired weight.
