From sports icons like Serena Williams to established A-listers like Vanessa Williams and Oprah Winfrey, celebrities are increasingly including GLP-1 drugs as part of their weight loss management experiences. This is an interesting shift that has seen celebrities talk more candidly about weight loss, moving away from ambiguous lifestyles.
For some time, the weight loss and weight gain experiences of famous people have been out in the open, with little being said about the processes behind the weight loss or weight gain.
This is no longer the case, as the wave of GLP-1 celebrity weight loss disclosures is out in the open, with many of them like actors, sports icons, and TV personalities publicly disclosing the names of GLP-1 drugs like Ozempic, Wegovy, Mounjaro, Zepbound, etc.
With more public figures attributing the change in weight to pregnancy, menopause, diabetes, or an ongoing struggle, the approach began to change. Simply stating the drug was a way to add context, not controversy.
Serena Williams and the Shift to More Open GLP-1 Weight Loss Disclosure
A commonly cited instance of a celebrity disclosing the use of a GLP-1 drug was when Serena Williams began to speak publicly regarding her own use of the drug after pregnancy.
She stated that, despite maintaining an elite training routine and a healthy eating schedule, the change in her weight was not responding as she would have hoped.
Williams would later reveal that she used the drug via a telehealth program as a way to add to the routines she was already using to improve her health. She stated that the weight was coming off gradually, as opposed to all at once, and that the change was more focused on the way she felt as opposed to the actual numbers.
Vanessa Williams and the Long-Term Usage of a GLP-1 Drug During Menopause
A commonly found information of the use of a GLP-1 drug was when Vanessa Williams revealed in early 2026 that she had been using the Mounjaro drug to assist with the change in her weight due to menopause, which had been occurring over the course of the last two years.
She stated publicly that the drug was helping, as her routines no longer produced the same effect as they once did. She noted that the change in her weight was a complex issue, as there was hormone therapy as well as the use of the drug to assist with the change in her weight during this time of her life.
Oprah Winfrey
She has also explained her experiences as a way to start, stop, and resume GLP-1 as a means of managing her process. The words that she has shared have emphasized the importance of the continuity of the process, self-management, and the fact that weight management is a process that involves adjustments.
Winfrey’s admissions about GLP-1 have also been part of shifting the attention of GLP-1 as a means of achieving results quickly. The fact that she has admitted to the need for weight management has helped create the words that GLP-1 is a useful tool of managing the process as opposed to the need for results.
Pop Stars and Performers Adding to the GLP-1 Conversation
Meghan Trainor has admitted to the fact that she has used Mounjaro as a way of managing her weight, finding balance and getting strong as opposed to focusing on the numbers that she has achieved.

Amy Schumer has stated that she has used GLP-1, stopped, and then started using Mounjaro because she wanted to manage her perimenopause and chronic pain.
Lizzo has confessed that she has used Ozempic as well as other GLP-1s to adjust her appetite.
These revelations, in total, add to the general awareness pertaining to the topic of GLP-1 celebrity weight loss. These pieces of information provide the topic of GLP-1 celebrity weight loss from different body types, genres, and stages of their lives instead of concentrating solely on the image and storyline.
Television and Reality Personalities: Bringing GLP-1 into the Open
Some of the most important platforms where the use of GLP-1 is currently being discussed include daytime television shows, late-night media shows, and reality television personalities. These individuals tend to discuss their weight loss and changes while they are already discussing their lives openly.
Andy Cohen has openly discussed his use of GLP-1 and how it was something that helped him change his perspective on food and his lifestyle.
Jonathan Van Ness also openly disclosed his use of GLP-1 to get rid of his binge eating and health problems. It was a very transformative experience for him.
Reality television personalities include Tori Spelling said that she used Mounjaro after trying other methods but failing to get the desired results.
Dolores Catania from Real Housewives of New Jersey, Jennifer Aydin from Real Housewives of Orange County and Lauren Manzo from Real Housewives of New Jersey have all openly admitted to using GLP-1.
Since they have already been openly talking about their lives on television to begin with, the fact that they have brought up the use of GLP-1 is given greater prominence.
Athletes and Media Personalities Expanding the GLP-1 Discussion
Celebrities such as athletes and media personalities also help in the expanding discussion of the use of the drug, especially among those who do not necessarily fall into the category of the stereotypical Hollywood celebrity.
Charles Barkley has shared his experience with the drug Mounjaro after years of trying to deal with his issues of being overweight.

Tracy Morgan has also shared his experience with the drug Ozempic, but only in his own signature way of being funny and talking about his lack of appetite, as well as the change that the drug has provided to his life.
If all these stories are put together, it seems to suggest that the issue of the GLP-1 celebrity weight loss is becoming something that the public knows, rather than something that the celebrities themselves are aware of, but the public is not.
How Celebrities Usually Describe What GLP-1 Medications Do
When the celebrity talks about the drug, the way in which the drug works on their body is quite simple and involves the fact that the drug has helped them to eat less and feel full more often, or has helped them to not think so much about their meals throughout the day.
There is not much science involved in the way in which the celebrity talks about the drug, but the drug has helped them to eat normally after years of trying to do so through dieting.

